Multiple Choice on Third line of defense of the Immune system

MCQ on Third line of defense

1. Third line of defense involves   

a) B Lymphocytes

b) T lymphocytes

c) Antigen presenting cells

d) All of the above

 

2. The cells that produce antibodies in third line of defence is the

a) B cells

b) Tc Cells

c) Th cells

d) Plasma cells of the B cells

 

3. Th cells can recognize only antigen that is bound to

a) antibodies

b) MHC Class I

c) MHC Class II

d) MHC Class I and II

 

4. Thymus dependent antigens can activate B cells

a) without Th cells involvement

b) with Tc cells involvement

c) with Th cells involvement

d) with Th cells and Tc cells involvement

 

5. The order of basic mechanisms of Third line of defence is

a) APC presenting antigen on MHC Class -->Th cell activation by IL2 secretion --> B cell and Tc cell activation

b) APC presenting antigen on MHC Class II-->Th cell activation by IL2 secretion --> B cell and Tc cell activation

c) APC presenting antigen on MHC Class II --> B cell and Tc cell activation --> Th cell activation by IL2 secretion

c) APC presenting antigen on MHC Class I --> B cell and Tc cell activation --> Th cell activation by IL2 secretion

 

6. Which of the following mechanisms in third line of defence is effective in imparting immunologic memory by memory cell production?

a) Th cell independent activation

b) Th cell dependent activation

c) Th cell independent activation of Tc cells

d) All of these

 

7. Which of the following is the incorrect statement with regard to B cell activation?

a) B cells on activation undergo proliferation and differentiation forming plasma cells that form antibodies

b) In Th cell dependent activation, B cell act as APC

c) Memory B cells are produced in Th cell independent activation

d) on activation, B cells proliferates by clonal selection

 

8. Which of the following cell is primarily involved in modulating, activating and regulating immune response in third line of defence?

a) B cells

b) T helper cells

c) T cytotoxic cells

d) APCs

 

9. Tc cells can recognize antigen that is bound to

a) antibodies

b) MHC Class I

c) MHC Class II

d) MHC Class I and II

 

10. Tc cells cause lysis of infected cells by means of

a) perforins

b) granyzymes

c) both a and b

d) apoptosis

 

11. The characteristic features of third line of defense are

a) Diversity

b) Specificity

c) Immunologic memory

d) all of these

More:

 First Line of defense

 Second line of defense

 

Answers:

1. d) All of the above

2. d) Plasma cells of the B cells

3. c) MHC Class II

4. c) with Th cells involvement

5. b) APC presenting antigen on MHC Class II->Th cell activation by IL2 secretion -> B cell and Tc cell activation

6. b) Th cell dependent activation

7. c) Memory B cells are produced in Th cell independent activation

8. b) T helper cells

9. b) MHC Class I

10. c) both a and b

11. All of these