1. The process of removal and replacement of damaged tissues or organs with healthy ones from a donor is called as
a) transplantationb) replacement therapyc) repair and replacementd) none of these
2. The transfer of individuals own tissue to another part of the body is called
a) autograftb) xenograftc) allograftd) syngeneic graft
3. The transfer of tissue between genetically identical individuals (like twins) is called
a) autograftb) xenograftc) allograftd) syngeneic graft
4. The transfer of tissue between individuals of different species is called
a) autograftb) xenograftc) allograftd) syngeneic graft
5. The transfer of tissue between genetically different individuals of same species is called
a) autograftb) xenograftc) allograftd) syngeneic graft
6. Which of the following has the maximum transplantation success rate
a) autograftb) xenograftc) allograftd) syngeneic graft
7. The major molecules responsible for rejection of transplant is
a)B cellsb) T cellsc) MHC moleculed) antibodies
8. Genes encoding cell surface glycoproteins that are required for antigen presentation to T cells and also responsible for rapid graft rejection is called as
a) MHC complexb) B cell complexc) T cell complexd)none of these
9. Which of the following statements are true regarding transplantation
a) The compatibility of MHC proteins of donor and recipient will determine the success of transplantationb) MHCs are just like fingerprints and all nucleated cells possess this fingerprintc) The compatibility of MHC/HLA proteins of donor and recipient will be high if they are genetically closely related and may lead to successful transplantation.d) all of these
10. In humans, MHC is called as
a) human MHCb) Homo MHCc) Human leucocyte antigen (HLA)d) all of the above
11. The genes for HLA proteins are clustered in the major histocompatibility complex located
Chromosome 6 |
a) on the short arm of chromosome 6b) on the long arm of chromosome 6c) on the short arm of chromosome10d) on the long arm of chromosome 10
12. The test that is done prior to transplantation surgery to determine the compatibility of MHC proteins between donar and recipient is called
a) MHC matchingb) MHC typingc) tissue typingd) blood HLA test
13. Cyclosporine is an immunosuppressive drug given to avoid transplant rejection which acts by
a) inhibition of T cellsb) inhibition of B cellsc) inhibition of immune systemd) inhibition of complement system
14.MHC class I is a cell surface molecule present on
MHC |
a) B cellsb) all nucleated cellsc) APCsd) T cells
15. MHC class II is a cell surface molecule present on
1. a) transplantationa) B cellsb) all nucleated cellsc) APCsd) T cells
2. a) autograft
3. d) syngeneic graft
4. b) xenograft
5. c) allograft
6. a) autograft
7. c) MHC molecule (Major histocompatibility complex)
8. a) MHC complex
9. d) all of these
10. c) Human leucocyte antigen (HLA)
11. a) on the short arm of chromosome 6
12. c) tissue typing
13. a) inhibition of T cells
14. b) all nucleated cells
15. c) APCs
Tags:
immunology mcqs
immunology multiple choice
MCQ on Immunology
MCQ on Transplantation
medical mcq
Multiple choice questions on Immunology
nclex Immune system physiology Questions