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| Complement system |
a) consists of 20 serum proteinsb) serum proteins acts as biological cascadec) both a and bd) are set of antibodies
2. Complement system is involved in
a) specific defenceb) non-specific defencec) both a and bd) none of these
3. Which of the following statements are true regarding complement activation
a) lysis of pathogen, tumor cells and allograftsb) production of mediators that attracts neutrophils to the site of inflammationc) opsonizationd) all of these
4. Classical pathway of complement system is activated by
a) antibody-antigen complexesb) antigenc) antigenic peptidesd) antigens bound to MHC
5. Alternate pathway of complement system is activated by
a) antibody-antigen complexesb) antigenc) microorganisms or its toxinsd) antigens bound to MHC
6. Classical pathway of complement system is involved in
a) specific defenceb) adaptive immunityc) both a and bd) non-specific defence
7. Alternate pathway of complement system is involved in
a) non-specific defenceb) innate immunityc) both a and bd) adaptive immunity
8. Which of the following is the central molecule in complement pathway
a) C1b) C2c) C3bd) C5
9. Cell lysis in complement pathway is initiated by
a) membrane destruction complexb) membrane degradation complexc) membrane attacking complexd) membrane lysis complex
10. MAC is
a) C5b6789 complexb) C5b5678 complexc) C5b5789 complexd) Protein polysaccharide complex
11. Which of the following is required for C1 activation
a) Cab) Mgc) Mnd) Zn
12. Which of the following is the most potent anaphylatoxin
a) C3ab) C4ac) C5ad) C1
13. In alternate pathway
a) factor b is involvedb) factor d is involvedc) both a and bd) Only factor f is involved
14. Biological role of complement system include
a) cytolysis and chemotaxisb) opsonisationc) anaphylotoxin and enhanced antibody productiond) all of these
15. Body’s own cells are protected from membrane attack complex by a surface glycoprotein called
a) MHCb) DAFc) TCRd) BCR
Learn more: Immunology Notes/ Immunology MCQs
Answers:
1. c) both a and b2.c) both a and b
3. d) all of these
4. a) antibody-antigen complexes
5. c) microorganisms or its toxins
6. c) both a and b
7. c) both a and b
8. c) C3b
9. c) membrane attacking complex
10. a) C5b6789 complex
11. a) Ca
12. c) C5a.( Anaphylotoxins: induces the release of inflammatory mediators like histamines from the mast cells. C3a, C4a and C5a are the anaphylatoxins of which C5a is the most potent)
13. c) both a and b
14. d) all of these
15. b) DAF (Human cells have a glycoprotein situated on the cell surface called as decay accelerating factor (DAF). DAF prevents the formation of membrane attack complex by destabilizing C3 and C5 convertase.)
14. d) all of these
15. b) DAF (Human cells have a glycoprotein situated on the cell surface called as decay accelerating factor (DAF). DAF prevents the formation of membrane attack complex by destabilizing C3 and C5 convertase.)
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MCQ on Complement system
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Multiple Choice Questions on Complement system
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