MCQ on Bioinformatics - Pioneers and Terminologies


1. The term bioinformatics was coined by
a) J D Watson
b) Margaret Dayhoff
c) Pauline Hogeweg
d) Frederic Sanger

2. Margaret Dayhoff developed the first protein sequence database called
a) SWISS PROT
b) PDB
c) Atlas of protein sequence and structure
d) Protein sequence databank

3. Step wise method for solving problems in computer science is called
a) flowchart
b) sequential design
c) procedure
d) algorithm

4. The first published completed gene sequence was of
a) M 13 phage
b) T 4 phage
c) φ X174
d) lambda phage

5. The term used to refer something ‘performed on computer or computer simulation”
a) dry lab
b) web lab
c) invitro
d) insilico

6. ‘Laboratory work using chemicals, drugs etc using water’ is referred as
a) dry lab
b) web lab
c) wet lab
d) insilico

7. ‘Laboratory work using computers and computer generated models generally offline’ is referred as
a) dry lab
b) web lab
c) wet lab
d) insilico

8. ‘Laboratory work using computers and associated web based analysis generally online’ is referred as
a) dry lab
b) web lab
c) wet lab
d) insilico

9. ‘invitro’  in latin means
a) within the glass
b) within the lab
c) outside the lab
d) outside the glass

10. NCBI was established in 

NCBI 
a) 1988
b) 1989
c) 1990
d) 1991

11. Application of bioinformatics include
a) data storage and management
b) drug designing
c) understand relationships between organisms
d) all of the above

12. The computational methodology that tries to find the best matching between two molecule, a receptor and ligand is called
a) molecular matching
b) molecular docking
c) molecular fitting
d) molecule affinity checking

13. Proteomics is the study of
a) set of proteins
b) set of proteins in a specific region of the cell
c) entire set of expressed proteins in a cell
d) none of these

14. The process of finding relative location of genes on a chromosome is called
a) gene tracing
b) genome mapping
c) genome walking
d) chromosome walking

15. A compound that has desirable properties to become a drug is called
a) lead
b) find
c) fit drug
d) fit compound

Answers

1-c
2-c
3-d
4-c
5-d
6-c
7-a
8-b
9-a
10-a
11-d
12-b
13-c
14-b
15-a
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