Multiple Choice Questions on Immunology - Humoral immunity

1. Humoral immunity is mediated by

a) B cells
b) macrophages
c) both a and b
d) phagocytes

2. Humoral immunity is also called as

a) antibody mediated immunity
b) non-specific immune response
c) antigen mediated immunity
d) all of these

3. B cell has receptor on its surface which is

a) monomeric IgM
b) dimeric IgM
c) monomeric IgG
d) B cell receptor

4. B cells upon activation by antigens

a) undergo clonal expansion followed by clonal selection
b) divides continuously
c) undergo clonal selection followed by clonal expansion
d) secrete antibodies

5. B cells differentiates to form

a) plasma cells
b) effector cells
c) plasma cells and memory B cells
d) none of these

6. Which of the following statement is incorrect regarding plasma cells

a) plasma cells are the effector cells
b) plasma cells secretes antibodies
c) The precursor of plasma cell is B cell
d) plasma cell has surface receptors

7. Origin and maturation of B cells takes place at

a) spleen
b) thymus
c) bone marrow
d) lymph nodes

8. The function of memory B cell is

a) antibody production
b) immunologic memory
c) regulated antibody production
d)none of these

9. B cells are

a) lymphocytes which are short lived
b) lymphocytes which are long lived
c) lymphocytes involved in non-specific defence
d) none of these

10. Generally antibodies produced against a pathogen is

a) monoclonal
b) homogenous
c) polyclonal
d)all of same specificity

11. Antibodies produced by plasma cells are

a) specific
b) produced against the epitope that triggered B cell activation
c) both a and b
d) diverse

12. Antibodies clear out antigens by

a) neutralization
b) precipitation
c) agglutination
d) all of these

13. Antibodies are

a) opsonins
b) lipoproteins
c) serum phagocytes
d) none of these

14. Any substance that promotes phagocytosis of antigens by binding to them are called as

a) opsonins
b) phagocytes
c) macrophages
d) interleukins

15. The phenomenon of selective proliferation of B cells in response to their interaction with the antigen is called

a) clonal expansion
b) monoclonal selection
c) clonal proliferation
d) clonal selection
Learn more: Immunology Notes, Immunology MCQs 

Answers:
1. a) B cells
2. a) antibody mediated immunity
3. a) monomeric IgM
4. c) undergo clonal selection followed by clonal expansion
5. c) plasma cells and memory B cells
6. d) plasma cell has surface receptors
7. c) bone marrow
8. b) immunologic memory
9. a) lymphocytes which are short lived
10. c) polyclonal
11. c) both a and b
12. d) all of these
13. a) opsonins
14. a) opsonins
15. d) clonal selection