Multiple Choice Questions on Immunology

1. An antigen is

a) A highly specific protein produced by the body in response to a foreign body
b) A chemical that inhibits the growth of micro organisms
c) An antibody produced by the body that stimulates the production of antibodies by the body’s immune system
d) A chemical substance that stimulates the production of antibodies by the body’s immune system

2. CD40 ligand is seen only on

a) Macrophages
b) Cytotoxic T cells
c) Helper T cells
d) Dentritic cells

3. High titres of antinuclear antibodies are indicative of

a) Parasitic infections
b) Fungal diseases
c) Autoimmune diseases
d) Bacterial diseases

4. Which of the following is an auto immune disease?

a) Type 1 Diabetes mellitus
b) Type 2 Diabetes mellitus
c) Haemophilia A
d) Sickle cell anemia

5. DNA vaccines elicit protective immunity against a microbial pathogen by activating:

a) Humoral immune system
b) Cellular immune system
c) Both a) and b)
d) None of these

6. Which is the first immunoglobulin class to be produced in a primary response to an antigen and also the first immunoglobulin to be synthesised by the neonates:

a) IgA b) IgB  c) IgD  d) IgM

7. In an immune response the type of cell which gets activated earliest is :

a) Killer T cells
b) Plasma cells
c) Helper T cells
d) Cytotoxic T cells

8. What is a characteristic of early stages of local inflammation?

a) Fever
b) Anaphylactic Shock
c) Release of histamine
d) Attack by cytotoxic T cells

9. An epitope associates with which part of an antibody?

a) The antibody binding site
b) The heavy chain constant regions only
c) Variable regions of a heavy chain and light chain combined
d) The light chain constant regions only

10. Which of the following is not true about helper T cells?

a) They function in cell mediated and humoral responses
b) They are activated by polysaccharide fragments
c) They bear surface CD4 molecules
d) They are subject to infection by HIV 

Learn more: Immunology MCQs / Immunology Notes 

Answers

1. d) A chemical substance that stimulates the production of antibodies by the body’s immune system
2. c) Helper T cells
3. c) Autoimmune diseases
4. a) Type 1 Diabetes mellitus
5. c) Both a) and b)
6. d) IgM
7. c) Helper T cells
8. c) Release of histamine
9. c) Variable regions of a heavy chain and light chain combined
10. b) They are activated by polysaccharide fragments