SET Biotechnology Questions 1-20
21. Which of the
following suits well with antigenic competition?
A) Involves competition between T-cell epitopes for the MHC groove.
B) Involves competition for available soluble antibodies.
C) Is unrelated to the concept of dominant and subdominant epitopes.
D) Can only occur with cryptic epitopes.
22. RAG-1 and RAG-2
enzymes effect the recombination of:
A) V(D)J to CH
B) H to L
C) V (D)J
D) VJ to Cl
23. Mendelian
susceptibility to mycobacterial infection does not involve the gene for:
A) IFNgR1. B) IL-12 p40. C) MEFV. D) IL-12RbI
24. Which is the
first of the following genes to be upregulated after T-cell activation?
A) Transferrin receptor B) c-myc C) VLA-1 D) Cytokine receptor
25. What is a
semi-synthetic drug?
A) A drug isolated from nature and used without any further modification
B) A drug made entirely in a lab from scratch
C) The structure of a drug half way through its preparation
D) A drug which has been part made by nature and part made in a lab
26. How many
different pollen genotypes are produced by F1 of the cross:
AAbbCCDD x aaBBccdd
A) 8 B) 16 C) 4 D) 32
27. If a rare
recessive X-linked allele has a frequency of 0.04 among females, what will
this allele frequency
among males?
A) 0.04 B) 0.0016 C) 0.2 D) 0.08
28. Thalidomide intake in the first trimester of pregnancy produces limbless children. The same condition has resulted from a mutation called phocomelia. Then thalidomide
syndrome is called as
a -------of phocomelia mutation
A) Phenocopy B) Expressivity C) Genotype D) Phenotype
29. ------ results in
creating new variation in a population.
A) Mutation B) Genetic drift C) Gene flow D) Random mating
30. Which among the
following produces 3' sticky ends?
A) Pst I B) BamHI C) EcoRI D) HindIII
31. ----- is the
cofactor of T4 DNA ligase.
A) NAD B) FAD C) ATP D) no cofactor requirement
32. A Lambda
replacement vector containing red and gam genes in the stuffer will need
additionally which
sequence for plaque formation after recombination
A) Psi B) Theta C) Chi D) Tau
33. ------ is a
co-dominant molecular marker.
A) RAPD B) AFLP C) ISSR D) RFLP
34. ------- is the
carbon source of MS medium.
A) sucrose B) glucose C) mannitol D) sorbitol
35. The disadvantage(s)
of using Lineweaver Burk plot:
A) Compared to other plots, departure from linearity is less obvious
B) Most points are found far to the right of y axis and large extrapolation is required to obtain Km and Vmax
C) Both A and B are correct
D) A is incorrect, but B is correct
36. Among the
following, which factor influences the Rf value the most?
A) Polarity of the solvent
B) Concentration of the extract to be separated
C) Temperature
D) Run time
37. Iduronic acid, a
constituent of heparin, is a stereoisomer of:
A) Gluconic acid B) Glucaric acid C) Glucuronic acid D) Muramic acid
38. When a cell is
incubated with ---- ATP synthesis increases.
A) Tween 20 B) Oligomycin C) 2, 4, dinitrophenol D) None of these
39. In ATP synthase,
two half channels that facilitates H+ ion shuttle are present in
A) α3β3 hexamer B) γε stalk C) Subunit a D) Subunit c
40. Mechanism based
inactivators of enzymes:
A) Alters the mechanism of action of the enzyme
B) Changes the inhibitor molecule to another species that strongly binds to the enzyme active site
C) Binds to a site in the enzyme that is different from the active site
D) None of these
Learn more: Topic Wise Biotechnology MCQ
Answers:
21.
22.
23.
24.
25.
26.
27.
28. A) Phenocopy
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
