Bioinformatics MCQ Questions and Answers

1. Which of the following computer language is used for artificial intelligence?

A) FORTRAN 

B) COBOL 

C) PROLOG 

D) C

2. The tool used for pairwise analysis of DNA sequences

A) ClustalW 

B) PROBCONS

C) MUSCLE 

D) BLAST

3. Which of the following public domain is/are open access data bases?

A) NCBI 

B) ExPASy

C) PDB 

D) All the above

Bioinformatics MCQ Questions

4. A data base of current sequence map of the human genome is called

A) OMIM 

B) HGMD

C) Golden path 

D) GeneCards

5. In the following common bioinformatic data bases, which contains protein 
sequence data?

A) Gene Bank 

B) EMBL-Bank

C) dbEST 

D) UniProt

6. FASTA program was first described by

A) Adach & Hasegawa 

B) Lipman & Pearson

C) Kyte and Dolittle 

D) Fitch & Margoliash

7. BLAST program is used in

A) DNA sequencing 

B) Amino acid sequencing

C) DNA bar coding 

D) Bioinformatics

8. Which among the following is a protein data base?

A) GEN BANK 

B) PIR 

C) DDBJ 

D) EMBL

9. The DNA and protein sequence alignment software package developed by David J Lipman and William R Pearson is

A) FASTA 

B) BLAST 

C) BioSCAN 

D) EMBOSS

10. In which format sequences submitted in Blast server?

A) FASTA 

B)FISTA

C) MmCIF

D)PDB file format

11. Which of the following is a protien data base?

A) DDBJ

B)EMBL

C) PIR

D)Gen Bank

12. PDB is an example for:

A) Primary nucleotide sequence database

B) Protein sequence database

C) Macromolecular 3D structure database

D) Sequence motif database

13. ----- is NOT a bioinformatic method to study gene expression.

A) t-SNE 

B) PCA

C) Hierarchical Clustering 

D) MALDI-TOF

14. Choose the statement which is true about Python and SPSS:

A) Both Python and SPSS are statistical software

B) Python is a statistical software and SPSS is a non-parametric paired t test

C) Python is a programming language and SPSS is a non-parametric paired t test

D) Python is a programming language and SPSS is statistical software 

15. Which of the following scientists created the first bioinformatics database?

A) Person

B) Margaret Oakley Dayhoff 

C) Michael J Dunn

D) Richard Durbin

16. The term Bioinformatics was coined by

A) J D Watson

B) Margaret Oakley Dayhoff 

C) Paulien Hogeweg 

D) Richard Durbin 

Answers
1. 
C) PROLOG 

2. D) BLAST

3. D) All the above

4. C) Golden path 

5. D) UniProt

6. B) Lipman & Pearson

7. D) Bioinformatics

8. B) PIR 

9. A) FASTA 

10. A) FASTA 

11. C) PIR

12. C) Macromolecular 3D structure database

13. D) MALDI-TOF

14. D) Python is a programming language and SPSS is statistical software

15. B) Margaret Oakley Dayhoff 

16. C) Paulien Hogeweg 

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