1. The class of antibody that is expressed on the surface of B-lymphocytes is
A) IgA
B) IgE
C) IgG
D) IgM
2. The type of immunological protection provided by plasma therapy is
A) Natural active
B) Natural passive
C) Artificial active
D) Artificial passive
3. Resistance of a population to the infection and pathogen spread due to the immunity among the large percentage of the population is called:
A) Passive immunity
B) Acquired immunity
C) Secondary immunity
D) Herd immunity
4. Assertion (A): Although antigen-antibody reactions are highly specific, in some cases antibody elicited by one antigen can cross-react with an unrelated antigen
Reason (R) :
Two different antigens can have equal number of epitopes
A) A is true
and R is the reason for A
B) A and R
are true but R is not the reason for A
C) A is true
but R is not true
D) A and R are not true
5. A
patient with myasthenia gravis disease produce auto-antibodies that bind with:
A) Histone proteins
B) Acetylcholine receptor
C) TSH receptor
D) Fc region of IgG
6. The
Papain enzyme digestion of IgG will yield:
A) Two Fab
fragments and one Fc fragment
B) One Fab
fragment and two Fc fragments
C) One Fab
fragment and one Fc fragment
D) Two heavy chains and two light chains
7. A complete virus particle, consisting of one or more molecules of DNA or RNA enclosed in a coat protein, is called a ------.
A) Viroid B) Virion C) Virusoid D) Prion
8. Choose
the correct statement about T lymphocytes:
A) Both CD4 and CD8 glycoproteins are expressed on the surface of all T lymphocytes
B) T cells displaying CD4 generally functions as TH cells, whereas those displaying CD8 generally functions as Tc cells
C) T cells displaying CD4 generally functions as TC cells, whereas those displaying CD8 generally functions as TH cells
D) Neither CD4 nor CD8 is expressed on T lymphocytes
9. Choose the statements which are correct about Monoclonal antibody:
1) They are specific for a single epitope
2) Comprises a mixture of antibodies, each specific for a particular epitope, produced from a variety of B-cell clones
3) It is easy to purify monoclonal antibody from polyclonal antibody preparation
4) Have research, diagnostic and therapeutic applications
A) Only 1 & 4 B) Only 1, 2 & 4 C) Only 1 & 3 D) All are correct
10. Choose
the correct statements:
1) TH cells
are class II MHC restricted and Tc cells are class I MHC restricted
2) TH cells
are class I MHC restricted and Tc cells are class II MHC restricted
3) All nucleated cells express class II MHC molecules and expression of class I MHC molecule is limited to antigen-presenting cells
4) All nucleated cells express class I MHC molecules and expression of class II MHC molecule is limited to antigen-presenting cells
A) Only 1 & 3 B) Only 2 & 3 C) Only 1 & 4 D) Only 2 & 4
Answers:
1. D) IgM
2. D) Artificial passive
3. D) Herd immunity
4. B) A and R are true but R is not the reason for A
5. B) Acetylcholine receptor
6. A) Two Fab fragments and one Fc fragment
7. B) Virion
8. B) T cells displaying CD4 generally functions as TH cells, whereas those displaying CD8 generally functions as Tc cells
9. A) Only 1 & 4
10. C) Only 1 & 4
