Biology Multiple Choice Questions and Answers for Different Competitive Exams

Multiple Choice Questions on Bioinformatics

1. Choose the set that represents the databases involved in the International Nucleotide Sequence Database Collaboration (INSDC)

a) DDBJ, ENA and NCBI-GENBANK

b) DDBJ, SWISS PORT and PROSITE

c) PDB, SWISS PORT and PROSITE

d) DDBJ, SWISSPORT and NCBI GENBANK

MCQ on Bioinformatics


2. The expansion of BLAST is:

a) Beginners Local Alignment Search Tool

b) Beginners Logical Alignment Search Tool

c) Basic Local Alignment Search Tool

d) Beginners Local Alignment Software Tool

3. The algorithm used in alignment of DNA sequences is

a) BLAST

b) Multialign

c) Needleman Wunsch

d) CLUSTAL

4. Which among the following is /are secondary biological databases?

1) DDBJ 2) PDB 3) Swiss PROT/UNIPORT 4) OMIM

a) 1 and 4 only

b) 1, 3, and 4 only

c) 1, 2, 3 and 4

d) 2 only

 5. Which among the following does not use sequence alignment?

      a) BLAST

      b) CLUSTAL

      c) Pair wise alignment                                                               

      d) Draw Tree

     6. Which is model organism database?

 a) GOLD

 b) PROMISE

 c) SGD

 d)SCOP

 7. Blast programme is used for

 a) Translate protein sequence.

 b) Translate DNA database

 c) Translate input sequence

 d) None of these

8. Widely used computer programs used in bioinformatics for multiple sequence alignment with command line interface

CLUSTAL W


 a) BLAST

 b) Target P

 c) CLUSTAL W

 d) Primer Express

9. Which of the following is not a sequence alignment tool?

 a) BLAST

 b) FASTA

 c) CLUSTAL

 d) RASMOL

10. As the E Value of a BLAST search becomes smaller

      a) The value K also becomes smaller.

      b)  The score tends to be larger.

      c) The probability p tends to be larger.

      d) The extreme value distribution becomes less skewed

11. EST division of EMBL database archives data in

      a) Only 5’ to 3’ direction.

      b) Only 3’ to 5’ direction.

      c) Both 5’ to 3’ and 3’ to 5’ to represent clones from two ends

      d)  Either 5’ to 3’ or 3’ to 5’

     12. Which of the following is a data bank exclusively for proteins

      a)  EMBL

      b) GEN BANK

      c)DDBJ

      d) PDB

      Learn more: Bioinformatics Multiple Choice  - Bioinformatics Glossary 

       1. a) DDBJ, ENA and NCBI-GENBANK

       2. c) Basic Local Alignment Search Tool

       3. c) Needleman Wunsch   

       4. c) 1, 2, 3 and 4

       5. d) Draw Tree

       6. c) SGD
  7. c) Translate input sequence

       8. c) CLUSTAL W
  9. d) RASMOL
  10. b)  The score tends to be larger.
  11.  a) Only 5’ to 3’ direction.
  12.  a)  EMBL


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