1.Which is a data retrieval system of NCBI?
a) SRS b)Entrez c)SAKURA d)DBGET
2. A
database of the current sequence map of the human genome is called
a) OMIM b) HGMD c)Golden path d)Gene cards
3. Which of the following public domain is /are open
access databases?
a) NCBI b) ExPASy c)PDB d)All the above
4. Which among the following is not a nucleic acid
database?
a) EMBL b) GenBank c)SWISS PROT d)DDBJ
5) BLAST is used:
a) to find similarity between sequences b) to align sequences
c)to design primers d)to amplify DNA
6. The tool
used for the pairwise analysis of DNA sequences?
a) Clustal W b) BLAST c)PROBCONS d)MUSCLE
7. Clustal Omega
program is used in
a) local alignment
b) global alignment
c)multiple sequence alignment
d)None of the above
8. Which of
the following is not a software used in bioinformatics?
a) EMBOSS b) AMPHORA c)ORANGE d)PROSITE
9. A
program to identify complete gene structures in genomic DNA
a) SWISSPORT b) BLAST c)PHYLIP d)GENSCAN
10. A bioinformatics tool that can be used to
characterize the Pan Genome
a) FDA b)BPGA c)PCR d)NRCS
11.Widely
used computer programs used in bioinformatics for multiple sequence alignment
with a command-line interface.
a) BLAST b)Target P c)CLUSTAL W d)Primer Express
12. Name the software package that can be used to phylogenetic analysis of plants
I. NTSYS II. Mesquite III. Darwin IV. Phylip
a) I, II and III
b) II, III and IV
c) I, III and IV
d) All of these
13. Choose the 'Nucleotide Sequence' databases.
a) EMBL, GenBank, NCBI
b) DDBJ, NCBI, PDB
c) Swiss Prot, EMBL, PDB
d) NCBI, MIPS, PIR
14. Protein sequence databases are the most comprehensive source of biological information on proteins. Select the nonprotein database from the given bioinformatics tool:
a) PIR
b) SWISS-PROT
c) TrEMBL
d) DDBJ
15. FASTA program was first described by
A) Adach & Hasegawa
B) Lipman & Pearson
C) Kyte and Dolittle
D) Fitch & Margoliash
16. Which of the following tools is used for the identification of motifs?
A) COPIA
B) BLAST
C) FASTA
D) PROSPECT
17. The computational methodology that tries to find the best matching between two molecules, a receptor and a ligand are called--
A) Molecular matching
B) Molecular fitting
C) Molecular Docking
D) Rasmol
Learn more: MCQ on Biological Database - Sequence Alignment
Answers:
1. b)Entrez
2. c)Golden path
3. d)All the above
4. c)SWISS PROT
5. a) to find similarity between sequences
6. b) BLAST
7. c)multiple sequence alignment
8. d)PROSITE
9. d)GENSCAN
10. b)BPGA
11. c)CLUSTAL W
12. d) All of these
13. a) EMBL, GenBank, NCBI
14. d) DDBJ
15. B) Lipman & Pearson
16. A) COPIA
17. C) Molecular Docking
