1. The largest secondary lymphoid organ is:
A)
Spleen
B)
Thymus
C)
MALT
D)
Lymph nodes
2.
The major immunoglobulin found in the colostrums of milk in nursing mothers:
A)
IgG
B)
IgM
C)
IgD
D)
IgA
3.
Match the following
Group
I Group II
a.
IgA 1. Basophils
b.
IgE 2. Crosses placenta
c.
IgG 3. Secretory component
d.
IgM 4. Pentamer
A)
a-3, b-1, c-2, d-4
B)
a-3, b-4 c-2, d-1
C)
a-2, b-3, c-1, d-4
D)
a-2, b-1, c-3, d-4
4.
For class I MHC, which of the following statements are correct?
1.
They are expressed on all nucleated cells
2.
They are made up of a heavy chain and a light chain
3.
They are essential for viral antigen recognition by cytotoxic cells
4.
The genes for HLA class I molecules are located on chromosome 6 and 15
A)
1 &3 only
B) 1
& 2 only
C) 2
& 3 only
D) 1,
3 & 4 only
5.
Interaction between a single paratope with an epitope is called:
A)
Cross-reaction
B)
Avidity
C)
Affinity
D)
Serological reactions
6.
Type I hypersensitivity is mediated by
A)
IgG
B)
IgE
C)
IgM
D)
IgD
7.
Match the following:
Group
I
Group II
a.
Isograft 1. Graft
from one body part to another of the same individual
b.
Allograft 2. Graft
between individuals from different species
c.
Xenograft 3. Graft between
genetically identical individuals
d.
Autograft 4. Graft
between genetically different individuals within a species
A)
a-4, b-2, c-3, d-1
B)
a-3, b-4, c-2, d-1
C)
a-3, b-2, c-4, d-1
D)
a-3, b-1, c-4, d-2
8.
Myasthenia gravis is an autoimmune disease caused by
A)
Autoantibodies against cell nuclei and intracytoplasmic cell constituents
B)
Autoantibodies against acetylcholine receptor on the myoneural junction
C)
Autoantibodies against cells of the zona glomerulosa
D)
Autoantibodies against parietal cells of the gastric mucosa
9.
Antibiotic used for the selection of hybridoma is:
A)
Neomycin
B)
Tetracycline
C)
Aminopterin
D)
Actinomycin D
10. A
drug used for the treatment of AIDS:
A)
Propanolol
B)
Azidothymidine
C)
Cimetidine
D)
Hirudin
11.
Interferons are:
A)
Proteins released by the cells in response to viral infection
B)
protein molecules that render
unattacked cells susceptible to viral attack
C) A specific type of immunoglobulin
D)
Both A and B
12.
The first recombinant antigen vaccine approved for human usage is for:
A)
HIV
B)
Hepatitis B
C)
Polio
D)
Influenza
Learn more: Topic Wise Immunology Multiple Choice
Answers:
1. A) Spleen
2. D) IgA
3. A) a-3, b-1, c-2, d-4
4. D) 1, 3 & 4 only
5. C) Affinity
6. B) IgE
7. B) a-3, b-4, c-2, d-1
8. B) Autoantibodies against acetylcholine receptor on the myoneural junction
9. C) Aminopterin
10. B) Azidothymidine
11. D) Both A and B
12. B) Hepatitis B
