1. Klenow fragment of DNA polymerase I lack :
A) 3’-5’ exonuclease activity
B) 3’-5’ polymerase activity
C) 5’-3’ exonuclease activity
D) 5’-3’ polymerase activity
2. The group of genes that
specify regions of the body plan of an embryo along the head-tail axis of
animals.
A)TATA box
B)Hox genes
C) Pribnow box
D)GC box
3. Carnegie 20 is :
(A) Transposon vector of Saccharomyces
(B) Transposon vector of E.coli
(C) Transposon vector of Bacillus spp
(D) Transposon vector of Drosophila
4. Formation of what type of chemical bond is catalyzed by DNA ligase
A) Phosphoester
B) Hydrogen
C) Glycosidic
D) Ester
5. Choose the mismatch
A. DNase I 1.Cleaves only ds DNA
B. Maxam-Gilbert method 2.Chemical modification of bases
C. Dideoxy terminator 3. Sanger method
D. Biotin 4. Water soluble vitamin
6. Which of the following is/are involved in the initiation of DNA replication?
(i) RhoA (ii) oriC (iii) Sigma factor (iv) DnaA
A) i,ii
B) ii,iii
C)iii,iv
D)ii,iv
7. The bacterial enzyme that changes positively supercoiled DNA into negatively
supercoiled DNA is
A) DNA helicase
B) DNA gyrase
C) Single stranded binding protein
D) Polymerase
8. What are known as “safe havens” during insertion of transposable elements?
A) Centromere regions
B) Retrotransposon regions
C) Heterochromatin regions
D) All these
9. P elements are transposable elements found in
A) Maize
B) Yeast
C) Drosophila
D) Arabdiopsis
10. The factor involved in the control of epigenetic gene expression in eukaryotes is?
A) RNA polymerase II
B) DNA methyltransferase
C) TF II D
D) TF II H
11. Which of the following is/are common to both prokaryotic and eukaryotic gene expression?
(i) Coupled transcription and translation
(ii) Post-translational modification
(iii) Genetic code
(iv) Presence of the sequence TATA in the promoter
A) i,ii,iii
B) iii, iv
C) i, iv
D)i, ii
Answer:
1. C) 5’-3’ exonuclease activity
2. B)Hox genes
3. (D) Transposon vector of Drosophila
4. A) Phosphoester
5. A. DNase I 1.Cleaves only ds DNA
6. D)ii,iv
7. B) DNA gyrase
8. D) All these
9. C) Drosophila
10. B) DNA methyltransferase
11. B)iii, iv
