Biology Multiple Choice Questions and Answers for Different Competitive Exams

MCQ on Immunology -Transplantation

1. The process of removal and replacement of damaged tissues or organs with healthy ones from a donor is called as
a) transplantation
b) replacement therapy
c) repair and replacement
d) none of these
2. The transfer of individuals own tissue to another part of the body is called
a) autograft
b) xenograft
c) allograft
d) syngeneic graft
3. The transfer of tissue between genetically identical individuals (like twins) is called
a) autograft
b) xenograft
c) allograft
d) syngeneic graft
4. The transfer of tissue between individuals of different species is called
a) autograft
b) xenograft
c) allograft
d) syngeneic graft
5. The transfer of tissue between genetically different individuals of same species is called
a) autograft
b) xenograft
c) allograft
d) syngeneic graft
6. Which of the following has the maximum transplantation success rate
a) autograft
b) xenograft
c) allograft
d) syngeneic graft
7. The major molecules responsible for rejection of transplant is
a)B cells
b) T cells
c) MHC molecule
d) antibodies
8. Genes encoding cell surface glycoproteins that are required for antigen presentation to T cells and also responsible for rapid graft rejection is called as
a) MHC complex
b) B cell complex
c) T cell complex
d)none of these
9. Which of the following statements are true regarding transplantation
a) The compatibility of MHC proteins of donor and recipient will determine the success of transplantation
b) MHCs are just like fingerprints and all nucleated cells possess this fingerprint
c) The compatibility of MHC/HLA proteins of donor and recipient will be high if they are genetically closely related and may lead to successful transplantation.
d) all of these
10. In humans, MHC is called as
a) human MHC
b) Homo MHC
c) Human leucocyte antigen (HLA)
d) all of the above
11. The genes for HLA proteins are clustered in the major histocompatibility complex located
Human chromosome 6
Chromosome 6
a) on the short arm of chromosome 6
b) on the long arm of chromosome 6
c) on the short arm of chromosome10
d) on the long arm of chromosome 10
12. The test that is done prior to transplantation surgery to determine the compatibility of MHC proteins between donar and recipient is called
a) MHC matching
b) MHC typing
c) tissue typing
d) blood HLA test
13. Cyclosporine is an immunosuppressive drug given to avoid transplant rejection which acts by
a) inhibition of T cells
b) inhibition of B cells
c) inhibition of immune system
d) inhibition of complement system
14.MHC class I is a cell surface molecule present on
MHC Class I and Class II
MHC 
a) B cells
b) all nucleated cells
c) APCs
d) T cells
15. MHC class II is a cell surface molecule present on
a) B cells
b) all nucleated cells
c) APCs
d) T cells
Answers
1. a) transplantation
2. a) autograft
3. d) syngeneic graft
4. b) xenograft
5. c) allograft
6. a) autograft
7. c) MHC molecule (Major histocompatibility complex)
8. a) MHC complex
9. d) all of these
10. c) Human leucocyte antigen (HLA)
11. a) on the short arm of chromosome 6
12. c) tissue typing
13. a) inhibition of T cells
14. b) all nucleated cells
15. c) APCs
For More : Immunology Notes /  Immunology MCQs 
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