Biology Multiple Choice Questions and Answers for Different Competitive Exams

Multiple Choice Questions on Translation

1. Genetic code is
a) the sequence of nitrogenous bases in mRNA molecule that codes for a protein
b) is a triplet code
c) is non-overlapping
d) all of these

2. Translation is the
eukaryotic transcription and translation
a) synthesis of DNA from a mRNA template
b) synthesis of protein from a mRNA template
c) synthesis of RNA from a mRNA template
d) synthesis of RNA from a DNA template

3. Translation occurs in the
a) nucleus
b) cytoplasm
c) nucleolus
d) lysosome

4. During translation, proteins are synthesized
a) by ribosomes using the information on DNA
b) by lysosome using the information on DNA
c) by ribosomes using the information on mRNA
d) by ribosomes using the information on rRNA

5. The enzyme involved in amino acid activation is
a) ATP synthetase
b) aminoacyl tRNA synthetase
c) aminoacyl mRNA synthetase
d) aminoacyl rRNA synthetase

6. Which of the following RNA molecules serves as an adaptor molecule during protein synthesis
a) rRNA
b) mRNA
c) tRNA
d) tRNA and mRNA

7. In Prokaryotes, the first amino acid in the polypeptide chain is
a) methionine
b) N-methyl methionine
c) N-formyl methionine
d) All of these

8. In Prokaryotes, the ribosomal binding site on mRNA is called
a) Hogness sequence
b) Shine-Dalgarno sequence
c) Pribnow sequence
d) TATA box

9. During translation, the role of enzyme peptidyl transferase is
a) transfer of phosphate group
b) amino acid activation
c) peptide bond formation between adjacent amino acids
d) binding of ribosome subunits to mRNA

10. Polysomes are
a) aggregation of ribosomes
b) aggregation of lysosomes
c) mRNA molecules to which many ribosomes are attached simultaneously
d) all of these

11. Which is the energy rich molecule required for initiation of translation
a) ATP
b) GTP
c) CTP
d) AMP

12. eRF1 is the release factor in eukaryotes that requires
a) ATP for its binding to ribosome
b) GTP for its binding to ribosome
c) ATP and GTP for its binding to ribosome
d) Mn2+for its binding to ribosome

13. In eukaryotes, translation is initiated by binding of ribosome to the
a) Pribnows box
b) Hogness box
c) 5’cap
d) poly A tail

14. hsp 60 and 70 are proteins involved in
a) initiation of translation
b) elongation of translation
c) termination of translation
d) protein folding

15. Tetracycline blocks protein synthesis by
a) inhibiting binding of aminoacyl tRNA to ribosome
b) inhibiting initiation of translation
c) inhibiting peptidyl transferase
d) inhibiting translocase enzyme

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Answers
1. b) is a triplet code
2. b) synthesis of protein from a mRNA template
3. b) cytoplasm
4. c) by ribosomes using the information on mRNA
5. b) aminoacyl tRNA synthetase
6. c) tRNA
7. c) N-formyl methionine
8. b) Shine-Dalgarno sequence
9. c) peptide bond formation between adjacent amino acids
10. c) mRNA molecules to which many ribosomes are attached simultaneously
11. b) GTP
12. b) GTP for its binding to ribosome
13. c) 5’cap
14. d) protein folding
15. a) inhibiting binding of aminoacyl tRNA to ribosome

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