Multiple Choice Questions on Sequence Alignment

1. The procedure of aligning two sequences by searching for patterns that is in the same order in the sequences
sequence alignment
a) sequence alignment
b) pair wise alignment
c) multiple sequence alignment
d) all of these

2. Alignment method suitable for aligning closely related sequence is
a) multiple sequence alignment
b) pair wise alignment
c) global alignment
d) local alignment

3. The alignment procedure that tries to align the entire sequence is
a) multiple sequence alignment
b) pair wise alignment
c) global alignment
d) local alignment

4. The alignment method suitable for finding out conserved patterns in DNA or protein sequences is
a) multiple sequence alignment
b) pair wise alignment
c) global alignment
d) local alignment
5. The procedure of aligning many sequences simultaneously is called
a) multiple sequence alignment
b) pair wise alignment
c) global alignment
d) local alignment

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6. Sequence alignment helps scientists
a) to trace out evolutionary relationships
b) to infer the functions of newly synthesized genes
c) to predict new members of gene families
d) all of these

7. The alignment procedure that tries to align regions with high level of matches without considering the alignment of rest of the sequences is
a) multiple sequence alignment
b) pair wise alignment
c) global alignment
d) local alignment

8. All are sequence alignment tools except
a) Rasmol
b) BLAST
c) FASTA
d) Clustal W

9. Which of the following is a sequence alignment tool provided by NCBI
a) Chime
b) BLAST
c) FASTA
d) Clustal W

10. Which of the following is a multiple sequence alignment tool?
a) Clustal W
b) Chime
c) Dismol
d) PDB
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Answers

1. b) pair wise alignment
2. c) global alignment
3. c) global alignment
4. d) local alignment
5. a) multiple sequence alignment
6. d) all of these
7. d) local alignment
8. a) Rasmol
9. b) BLAST
10. a) Clustal W

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