Multiple Choice Questions on Mutation

1. Point mutation involves
Mutation
a) deletion
b) insertion
c) duplication
d) change in single base pair

2. Transition type of gene mutation is caused when
a) GC is replaced by TA
b) CG is replaced by GC
c) AT is replaced by CG
d) AT is replaced by GC

3. Gene mutation occurs at the time of
a) DNA repair
b) DNA replication
c) Cell division
d) RNA transcription

4. The action of ultraviolet radiation on DNA to induce mutation is the
a) formation of thymine dimers
b) methylation of base pairs
c) deletion of base pairs
d) addition of base pairs

5. X rays causes mutation by
a) deletion
b) transition
c) transversion
d) base substitution

6. Which of the following have been developed by mutation?
a) Knol knol variety of castor
b) Aruna variety of barley
c) Erectiferum variety of cabbage
d) Reimei variety of Rice

7. Normally DNA molecule has A-T, G-C pairing. However, these bases can exist in alternative valency status, owing to rearrangements called
a) point mutation
b) frameshift mutation
c) analogue substitution
d) tautomerization mutation

8. In mutational event, when adenine is replaced by guanine, it is a case of
a) transition
b) transcription
c) transversion
d) frameshift mutation
9. Muller was first to produce induced mutations in ---- by exposing them to X rays
a) Paramecium
b) Arabidopsis
c) Drosophila
d) Xenopus

10. Which of the following is not ionizing radiations are
a) X rays
b) UV rays
c) cosmic rays
d) alpha rays 

11. Ames test is based on: 
a) Reversion of mutations in the histidine (his) operon in the genetically altered strains of Salmonella typhimurium 
b) Reversion of mutations in the lactose (lac) operon in the genetically altered strains of Salmonella typhimurium 
c) Reversion of mutations in the tryptophan(trp) operon in the genetically altered strains of Salmonella typhimurium
d) Reversion of mutations in the arabinose(ara) operon in the genetically altered strains of Salmonella typhimurium

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Answers
1. d) change in single base pair
2. d) AT is replaced by GC
3. b) DNA replication
4. a) formation of thymine dimers
5. a) deletion
6. d) Reimei variety of Rice
7. d) tautomerization mutation
8. a) transition
9. c) Drosophila
10. b) UV rays
11.  a) Reversion of mutations in the histidine (his) operon in the genetically altered strains of Salmonella typhimurium 

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